ERCC5 anticorps (N-Term)

N° du produit ABIN2785635

Détail du produit anti-ERCC5 anticorps

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC5 est non-conjugé

Application: Western Blotting (WB)

Séquence: HSGHIRRQYE DEGGFLKEVE SRRVVSEDTS HYILIKGIQA KTVAEVDSES

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ERCC5

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERCC5

Antigène: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Autre désignation: ERCC5 (ERCC5 Produits)

Synonymes: anticorps COFS3, anticorps ERCM2, anticorps UVDR, anticorps XPG, anticorps XPGC, anticorps cofs3, anticorps ercm2, anticorps uvdr, anticorps xpg, anticorps xpgc, anticorps Xpg, anticorps ERCC excision repair 5, endonuclease, anticorps excision repair cross-complementation group 5 L homeolog, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 5, anticorps ERCC5, anticorps ercc5.L, anticorps Ercc5

Sujet: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.
Protein Interaction Partner: UBC, CDK7, GTF2H1, POLR2A, EWSR1, ERCC6, SUMO2, PIDD1, BCL6, TAF10, ERCC3, NTHL1, GTF2H4, PCNA, ERCC2,
Protein Size: 1180

Poids moléculaire: 130 kDa

ID gène: 2073

UniProt: P28715

Pathways: Réparation de l'ADN