NLRP1 anticorps (N-Term)
Aperçu rapide pour NLRP1 anticorps (N-Term) (ABIN2785731)
Antigène
Voir toutes NLRP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- NLRP1 Antibody - N-terminal region
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Séquence
- DTQEPRIVIL QGAAGIGKST LARQVKEAWG RGQLYGDRFQ HVFYFSCREL
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Homologie
- Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against NLRP1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54478-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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Autre désignation
- NLRP1
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Sujet
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Background Information: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like
Gene Name: NLR family, pyrin domain containing 1
Alternative Symbols: NAC, JRRP, MSPC, AIADK, CARD7, CIDED, NALP1, SLEV1, DEFCAP, PP1044, VAMAS1, CLR17.1, DEFCAP-L/S
Protein Name: NACHT, LRR and PYD domains-containing protein 1
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Poids moléculaire
- 165 kDa
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ID gène
- 22861
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NCBI Accession
- NP_001028225
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UniProt
- Q9C000
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Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
Antigène
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