ACADVL anticorps (N-Term)

N° du produit ABIN2785735

Détail du produit anti-ACADVL anticorps

Antigène: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACADVL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: RPYAGGAAQE SKSFAVGMFK GQLTTDQVFP YPSVLNEEQT QFLKELVEPV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against ACADVL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACADVL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 633 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ACADVL (ABIN2785735)

Yoon, Kang, Ryu, Poo: "Identification of tyrosine-nitrated proteins in HT22 hippocampal cells during glutamate-induced oxidative stress." dans: Cell proliferation, Vol. 43, Issue 6, pp. 584-93, (2010) (PubMed).

Détails sur ACADVL

Antigène: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Autre désignation: ACADVL (ACADVL Produits)

Synonymes: anticorps ACAD6, anticorps LCACD, anticorps VLCAD, anticorps vlcad, anticorps fb52d04, anticorps wu:fb52d04, anticorps wu:fc75e01, anticorps zgc:64067, anticorps acyl-CoA dehydrogenase very long chain, anticorps acyl-Coenzyme A dehydrogenase, very long chain, anticorps acyl-CoA dehydrogenase, very long chain, anticorps ACADVL, anticorps Acadvl, anticorps acadvl

Sujet: ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in ACADVL protein reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: ACAD6, LCACD, VLCAD
Protein Interaction Partner: EEF2K, GPHN, RPSA, ATF2, CDH1, INTS9, ATP5L, UBC, SOCS3, ICT1, ACADVL,
Protein Size: 633

Poids moléculaire: 64 kDa

ID gène: 37

NCBI Accession: NM_001033859, NP_001029031

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process