FBXO8 anticorps (Middle Region)
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- Antigène Voir toutes FBXO8 Anticorps
- FBXO8 (F-Box Protein 8 (FBXO8))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FBXO8 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EFFRHIHAPE ERGEYLETLI TKFSHRFCAC NPDLMRELGL SPDAVYVLCY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against FBXO8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human FBXO8
- Top Product
- Discover our top product FBXO8 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 319 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- FBXO8 (F-Box Protein 8 (FBXO8))
- Autre désignation
- FBXO8 (FBXO8 Produits)
- Synonymes
- anticorps FBXO8, anticorps T24I21.22, anticorps T24I21_22, anticorps zgc:136842, anticorps FBS, anticorps FBX8, anticorps Fbx8, anticorps F-box protein 8, anticorps F-box and associated interaction domains-containing protein, anticorps F-box protein 8 L homeolog, anticorps FBXO8, anticorps fbxo8, anticorps AT2G16810, anticorps fbxo8.L, anticorps Fbxo8
- Sujet
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FBXO8 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO8 belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Alias Symbols: DC10, FBS, FBX8
Protein Interaction Partner: SKP1, ELAVL1, MYC, CUL1, UBC, ARF6,
Protein Size: 319 - Poids moléculaire
- 37 kDa
- ID gène
- 26269
- NCBI Accession
- NM_012180, NP_036312
- UniProt
- Q9NRD0
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