PTPN22 anticorps (Middle Region)

N° du produit ABIN2785942

Détail du produit anti-PTPN22 anticorps

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN22 est non-conjugé

Application: Western Blotting (WB)

Séquence: TAPRIDDEIP PPLPVWTPES FIVVEEAGEF SPNVPKSLSS AVKVKIGTSL

Homologie: Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%, Yeast: 82%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PTPN22. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PTPN22

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PTPN22

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Autre désignation: PTPN22 (PTPN22 Produits)

Synonymes: anticorps 70zpep, anticorps PEP, anticorps Ptpn8, anticorps LYP, anticorps LYP1, anticorps LYP2, anticorps PTPN8, anticorps protein tyrosine phosphatase, non-receptor type 22 (lymphoid), anticorps protein tyrosine phosphatase, non-receptor type 22, anticorps Ptpn22, anticorps PTPN22

Sujet: This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: LYP, PEP, LYP1, LYP2, PTPN8
Protein Size: 563

Poids moléculaire: 61 kDa

ID gène: 26191

NCBI Accession: NM_001193431, NP_001180360

UniProt: Q9Y2R2