GNAO1 anticorps (Middle Region)

N° du produit ABIN2786202

Détail du produit anti-GNAO1 anticorps

Antigène: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Épitope: Middle Region

Reactivité: Souris, Humain, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Mouton, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNAO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: CDVVSRMEDT EPFSAELLSA MMRLWGDSGI QECFNRSREY QLNDSAKYYL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GNAO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GNAO1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 354 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GNAO1 (ABIN2786202)

Zupancic, Blejec, Herman, Veber, Verbovsek, Korsic, Knezevic, Rozman, Turnsek, Gruden, Motaln: "Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach." dans: Radiology and oncology, Vol. 48, Issue 3, pp. 257-66, (2014) (PubMed).

Détails sur GNAO1

Antigène: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Autre désignation: GNAO1 (GNAO1 Produits)

Synonymes: anticorps G-ALPHA-o, anticorps GNAO, anticorps AW050213, anticorps Galphao, anticorps Gnao, anticorps alphaO, anticorps gnao1, anticorps wu:fq26h05, anticorps zgc:73315, anticorps RATBPGTPC, anticorps XGalpha01, anticorps gnao1-A, anticorps zgc:73153, anticorps G protein subunit alpha o1, anticorps guanine nucleotide binding protein, alpha O, anticorps guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a, anticorps G protein subunit alpha o1 L homeolog, anticorps Guanine nucleotide-binding protein G(o) subunit alpha, anticorps guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b, anticorps GNAO1, anticorps Gnao1, anticorps gnao1a, anticorps gnao1.L, anticorps goa-1, anticorps gnao1b

Sujet: Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.
Alias Symbols: DKFZp686O0962, G-ALPHA-o, GNAO
Protein Interaction Partner: UBC, ADRA2A, BAG3, Htt, RGS9, GABBR1, Haus4, RGS1, RIC8A, DCTN2, KLHL3, SCN8A, PDE6G, CRHR1, GPSM2, HRH4, NGB, S1PR5, RGS19, GRM6, FFAR2, TSHR, RGS5, RGS10, RGS7, RGS4, RGS16, RGS14, PTPRU, CCR5, NUCB1, PDE6H, CACNA1B, OPRM1, OPRD1, GNAO1, GNAI1, ADRA2C,
Protein Size: 354

Poids moléculaire: 40 kDa

ID gène: 2775

NCBI Accession: NM_138736, NP_620073

UniProt: B3KP89

Pathways: G-protein mediated Events