PRKACB anticorps (N-Term)

N° du produit ABIN2786690

Cet anticorps anti-PRKACB Polyclonal Lapin (ABIN2786690) détecte spécifiquement PRKACB dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien.

Aperçu rapide pour PRKACB anticorps (N-Term) (ABIN2786690)

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKACB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRKACB anticorps

Épitope: N-Term

Fonction: PRKACB Antibody - N-terminal region

Séquence: MGNAATAKKG SEVESVKEFL AKAKEDFLKK WENPTQNNAG LEDFERKKTL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRKACB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKACB

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56415-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRKACB

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Autre désignation: PRKACB

Sujet:

Targeted Subunit: beta

Background Information: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.

Gene Name: Protein kinase, cAMP-dependent, catalytic, beta

Alternative Symbols: CAFD2, PKACB, PKA C-beta

Protein Name: cAMP-dependent protein kinase catalytic subunit beta

Poids moléculaire: 28kDa

ID gène: 5567

NCBI Accession: NP_997461

UniProt: P22694

Pathways: AMPK Signaling, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism