PRKACB anticorps (N-Term)

N° du produit ABIN6243845

Détail du produit anti-PRKACB anticorps

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Épitope: AA 14-43, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKACB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PKA C-beta (PRKACB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human PKA C-beta (PRKACB).

Clone: RB3546

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PRKACB

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Autre désignation: PKA C-beta (PRKACB) (PRKACB Produits)

Synonymes: anticorps PKACB, anticorps XPKAbeta, anticorps kin-1, anticorps pkacb, anticorps prkacba, anticorps PRKACB, anticorps prkacb, anticorps wu:fz54b03, anticorps zgc:110804, anticorps Pkacb, anticorps protein kinase cAMP-activated catalytic subunit beta, anticorps protein kinase cAMP-activated catalytic subunit beta S homeolog, anticorps protein kinase, cAMP-dependent, catalytic, beta, anticorps protein kinase, cAMP-dependent, catalytic, beta b, anticorps protein kinase, cAMP dependent, catalytic, beta, anticorps PRKACB, anticorps prkacb.S, anticorps prkacb, anticorps Prkacb, anticorps prkacbb

Sujet: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.

Poids moléculaire: 40623

NCBI Accession: NP_001229786, NP_001229787, NP_001229788, NP_001229789, NP_001229790, NP_001229791, NP_002722, NP_891993, NP_997461

UniProt: P22694

Pathways: AMPK Signaling, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism