RFC1 anticorps (Middle Region)

N° du produit ABIN2786753

Détail du produit anti-RFC1 anticorps

Antigène: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFC1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AQAIYASVLP GELMRGYMTQ FPTFPSWLGK HSSTGKHDRI VQDLALHMSL

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RFC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RFC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1147 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RFC1

Antigène: RFC1 (Replication Factor C (Activator 1) 1, 145kDa (RFC1))

Autre désignation: RFC1 (RFC1 Produits)

Synonymes: anticorps A1, anticorps MHCBFB, anticorps PO-GA, anticorps RECC1, anticorps RFC, anticorps RFC140, anticorps AtRFC1, anticorps replication factor C 1, anticorps replication factor C1, anticorps 140kDa, anticorps Alp145, anticorps Recc1, anticorps Replication factor C1, anticorps si:dkey-170e5.1, anticorps zgc:162875, anticorps replication factor C subunit 1, anticorps replication factor C1, anticorps replication factor C (activator 1) 1, anticorps DNA replication factor C complex subunit Rfc1, anticorps RFC1, anticorps Rfc1, anticorps rfc1

Sujet: The protein encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability.
Alias Symbols: A1, MGC51786, MHCBFB, PO-GA, RECC1, RFC, RFC140
Protein Interaction Partner: SPRTN, UBC, PCNA, RPA3, RPA2, RPA1, YWHAQ, SMC1A, RFC4, NOTCH1, WDR18, RBM14, RFC5, RFC3, RFC2, LAMP2, MYOC, SIRT7, SUMO2, HDGF, RAD17, CSNK2B, tat, SAP25, ZSCAN1, SSBP3, PMS1, CEBPA, BRCA1, RFC1, BRD4, HDAC1, CASP3, TCEAL1, CCND1, RELA, CDK4, CHTF18, SMA
Protein Size: 1147

Poids moléculaire: 128 kDa

ID gène: 5981

NCBI Accession: NM_002913, NP_002904

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA, Dicarboxylic Acid Transport