NLRP2 anticorps (C-Term)

N° du produit ABIN617070

Cet anticorps anti-NLRP2 Polyclonal Lapin (ABIN617070) détecte spécifiquement NLRP2 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NLRP2 anticorps (C-Term) (ABIN617070)

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NLRP2 anticorps

Épitope: C-Term

Séquence: FETLTCSSGT LRTLRLKIDD FNDELNKLLE EIEEKNPQLI IDTEKHHPWA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NLRP2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NLRP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1062 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NLRP2

Antigène: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Autre désignation: NLRP2

Sujet: NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1, MIM 147678) by Toll-like receptors (see TLR4, MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).
Alias Symbols: CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Protein Interaction Partner: SUGT1, APP, FAF1, PYCARD, IKBKG, IKBKB, CHUK, HSP90AA1, UBC, MRE11A, PYDC2, CARD8,
Protein Size: 1062

Poids moléculaire: 120 kDa

ID gène: 55655

NCBI Accession: NM_017852, NP_060322

UniProt: Q9NX02

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome