GTF2I anticorps (Middle Region)

N° du produit ABIN2787508

Détail du produit anti-GTF2I anticorps

Antigène: GTF2I (General Transcription Factor III (GTF2I))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2I est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: INNQLVDQSE SEGPVIQESA EPSQLEVPAT EEIKETDGSS QIKQEPDPTW

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GTF2I. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GTF2I

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 998 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GTF2I (ABIN2787508)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur GTF2I

Antigène: GTF2I (General Transcription Factor III (GTF2I))

Autre désignation: GTF2I (GTF2I Produits)

Synonymes: anticorps BAP135, anticorps BTKAP1, anticorps DIWS, anticorps GTFII-I, anticorps IB291, anticorps SPIN, anticorps TFII-I, anticorps WBS, anticorps WBSCR6, anticorps Gtf2ird1, anticorps 6030441I21Rik, anticorps BAP-135, anticorps GtfII-I, anticorps Spin, anticorps bap-135, anticorps bap135, anticorps btkap1, anticorps diws, anticorps gtfii-i, anticorps ib291, anticorps spin, anticorps tfii-i, anticorps wbs, anticorps wbscr6, anticorps gtf2i, anticorps gtf2i.L, anticorps general transcription factor IIi, anticorps general transcription factor II I, anticorps general transcription factor IIi S homeolog, anticorps GTF2I, anticorps Gtf2i, anticorps gtf2i, anticorps gtf2i.S

Sujet: GTF2I is a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. The exon(s) encoding 5' UTR has not been fully defined, but this gene is known to contain at least 34 exons, and its alternative splicing generates 4 transcript variants. This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Four transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BAP-135, BAP135, BTKAP1, DIWS, IB291, SPIN, TFII-I, WBS, WBSCR6, GTFII-I
Protein Interaction Partner: TP53, ZMYM3, PIAS2, TUBG1, TRAF6, SUMO2, SUMO3, AP2B1, DPY30, GCC1, MTUS2, MDM2, UBC, SUMO1, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, CTPS2, WARS, RPL28, RAD23B, PRPS2, PRKDC, NUCB1, METTL1, ADSL, FBXO6, UBD, CBX2, TAB2, AP4S1, CBX4, MAPK12, C4BPA, MAP3K3, SLU
Protein Size: 998

Poids moléculaire: 112 kDa

ID gène: 2969

NCBI Accession: NM_032999, NP_127492

UniProt: P78347