ERK2 anticorps (C-Term)

N° du produit ABIN2787870

L’anticorps anti-ERK2 Polyclonal Lapin est utilisé pour la détection de ERK2 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye et Chévre. Il a été validé pour WB.

Aperçu rapide pour ERK2 anticorps (C-Term) (ABIN2787870)

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ERK2 anticorps

Épitope: C-Term

Séquence: PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MAPK1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 360 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ERK2

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Autre désignation: MAPK1

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Alias Symbols: ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Protein Interaction Partner: Eif4ebp1, ATF2, RPS6KA3, RAF1, PTGDR, MAP2K6, MAP2K1, MAPK3, HDAC6, TP53, NEDD8, DGCR8, HMGB1, NAV1, PDCD6IP, CEP350, MAPK12, RPS6KA2, MAPK1, PDE4D, MBP, KRAS, SQSTM1, CUEDC2, GAB2, BRAF, RPS6KA1, MAP2K4, MAP2K2, ELK1, NOXA1, TIAL1, GADD45A, MAP3K10, SMAD
Protein Size: 360

Poids moléculaire: 41 kDa

ID gène: 5594

NCBI Accession: NM_138957, NP_620407

UniProt: P28482

Pathways: Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins