COL1A1 anticorps (C-Term)

N° du produit ABIN2788299

Détail du produit anti-COL1A1 anticorps

Antigène: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL1A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: YRADDANVVR DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against COL1A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human COL1A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1464 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur COL1A1

Antigène: COL1A1 (Collagen, Type I, alpha 1 (COL1A1))

Autre désignation: COL1A1 (COL1A1 Produits)

Synonymes: anticorps OI4, anticorps Col1a-1, anticorps Cola-1, anticorps Cola1, anticorps Mov-13, anticorps Mov13, anticorps COLIA1, anticorps col1a1, anticorps MGC52532, anticorps COL1A1, anticorps COL1A2, anticorps alpha1(I), anticorps cb21, anticorps sb:cb21, anticorps sb:cb384, anticorps wu:fa99c12, anticorps wu:fb02c06, anticorps alpha3(I), anticorps col1a3, anticorps hm:zeh0348, anticorps wu:fa95h05, anticorps wu:fd02a10, anticorps wu:fj59a10, anticorps collagen type I alpha 1 chain, anticorps collagen, type I, alpha 1, anticorps collagen, type I, alpha 1 S homeolog, anticorps collagen alpha-1(I) chain, anticorps collagen type I alpha 2 chain, anticorps collagen, type I, alpha 1a, anticorps collagen 1a1, anticorps collagen, type I, alpha 1b, anticorps COL1A1, anticorps Col1a1, anticorps col1a1.S, anticorps LOC397571, anticorps COL1A2, anticorps col1a1a, anticorps col1a1, anticorps col1a1b

Sujet: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Alias Symbols: OI4
Protein Interaction Partner: PDGFB, PDGFA, COL1A2, COL1A1, CAPN1, UBC, BRCA1, BARD1, C12orf57, RNH1, ATP13A2, ELAVL1, ACHE, TMPRSS6, P4HB, PAK1, HTRA1, MATN2, PRELP, TGFBI, BGN, VWF, ITGA2, DDR2, THBS1, TXN, SPARC, CD36, FGF7, IGFBP3, ITGA5, FN1, NID1, DCN, CD93, MMP9, MMP2, COL7A1,
Protein Size: 1464

Poids moléculaire: 137 kDa

ID gène: 1277

NCBI Accession: NM_000088, NP_000079

UniProt: P02452

Pathways: Sensory Perception of Sound, Autophagy, Growth Factor Binding