SYK anticorps (Middle Region)

N° du produit ABIN971831

Détail du produit anti-SYK anticorps

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Épitope: Middle Region

Reactivité: Humain, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYK est non-conjugé

Application: Western Blotting (WB)

Séquence: RIKSYSFPKP GHRKSSPAQG NRQESTVSFN PYEPELAPWA ADKGPQREAL

Homologie: Horse: 85%, Human: 100%, Pig: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SYK. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 635 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SYK

Antigène: SYK (Spleen tyrosine Kinase (SYK))

Autre désignation: SYK (SYK Produits)

Synonymes: anticorps p72-Syk, anticorps Sykb, anticorps p72syk, anticorps spleen associated tyrosine kinase, anticorps spleen tyrosine kinase, anticorps syk, anticorps SYK, anticorps Syk

Sujet: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DKFZp313N1010, FLJ25043, FLJ37489, p72-Syk
Protein Interaction Partner: SH2D2A, TRAF6, STAT3, USP25, IL17RA, TRAF3IP2, PTPRO, UBC, FCGR3A, TICAM1, TLR9, TBK1, TRAF3, TLR4, TLR3, MAP3K7, MYD88, SRC, SYK, UBASH3B, VCAM1, ITGA4, ERBB4, ERBB3, ERBB2, EGFR, APP, SH3BP2, MAPT, TUBB, VAV2, VAV1, PIK3CG, BLNK, CBL, BTK, PIK3R1, TRAIP
Protein Size: 635

Poids moléculaire: 72 kDa

ID gène: 6850

NCBI Accession: NM_003177, NP_003168

UniProt: P43405

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling