MMACHC anticorps (C-Term)

N° du produit ABIN2788885

Détail du produit anti-MMACHC anticorps

Antigène: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMACHC est non-conjugé

Application: Western Blotting (WB)

Séquence: IALLEGFNFH WRDWTYRDAV TPQERYSEEQ KAYFSTPPAQ RLALLGLAQP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MMACHC. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 282 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MMACHC

Antigène: MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))

Autre désignation: MMACHC (MMACHC Produits)

Synonymes: anticorps cblC, anticorps RP11-291L19.3, anticorps RGD1310806, anticorps 1810037K07Rik, anticorps methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria, anticorps methylmalonic aciduria cblC type, with homocystinuria, anticorps MMACHC, anticorps Mmachc

Sujet: The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC.
Alias Symbols: DKFZp564I122, FLJ25671, RP11-291L19.3, cblC
Protein Interaction Partner: MMADHC, UBC,
Protein Size: 282

Poids moléculaire: 31 kDa

ID gène: 25974

NCBI Accession: NM_015506, NP_056321

UniProt: Q9Y4U1