PFKFB1 anticorps (C-Term)

N° du produit ABIN2788934

Détail du produit anti-PFKFB1 anticorps

Antigène: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKFB1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EEMTYEEIQE HYPEEFALRD QDKYRYRYPK GESYEDLVQR LEPVIMELER

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PFKFB1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 471 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PFKFB1

Antigène: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Autre désignation: PFKFB1 (PFKFB1 Produits)

Synonymes: anticorps zgc:55328, anticorps wu:fi11h10, anticorps PFKFB1, anticorps F6PK, anticorps HL2K, anticorps PFRX, anticorps Pfkfb01, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1, anticorps 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog, anticorps 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, anticorps pfkfb1, anticorps PFKFB1, anticorps pfkfb1.S, anticorps LOC100475853, anticorps Pfkfb1

Sujet: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
Alias Symbols: F6PK, HL2K, MGC116715, MGC116717, PFRX
Protein Interaction Partner: PFKFB1, Prkaa2, PRKCA, PRKACA, APP, AKT1, MAPK3,
Protein Size: 471

Poids moléculaire: 54 kDa

ID gène: 5207

NCBI Accession: NM_002625, NP_002616

UniProt: P16118

Pathways: Regulation of Carbohydrate Metabolic Process