SPHK1 anticorps (Middle Region)

N° du produit ABIN2789510

Cet anticorps anti-SPHK1 est un anticorps Lapin Polyclonal détectant SPHK1 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre et Lapin.

Aperçu rapide pour SPHK1 anticorps (Middle Region) (ABIN2789510)

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPHK1 anticorps

Épitope: Middle Region

Séquence: DVDLESEKYR RLGEMRFTLG TFLRLAALRT YRGRLAYLPV GRVGSKTPAS

Homologie: Cow: 93%, Dog: 93%, Goat: 77%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SPHK1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 384 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPHK1

Antigène: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Autre désignation: SPHK1

Sujet: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: SPHK
Protein Interaction Partner: UBC, BIRC3, MBTPS1, TRAF6, RARG, EP300, SPHKAP, RPS6KC1, CTNND2, TRAF2, LYN, FYN, CTSB,
Protein Size: 384

Poids moléculaire: 42 kDa

ID gène: 8877

NCBI Accession: NM_001142601, NP_001136073

UniProt: Q9NYA1

Pathways: VEGF Signaling