HRPT2 anticorps (C-Term)

N° du produit ABIN2789577

Détail du produit anti-HRPT2 anticorps

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HRPT2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KQGCQRENET LIQRRKDQMQ PGGTAISVTV PYRVVDQPLK LMPQDWDRVV

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CDC73. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 531 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HRPT2

Antigène: HRPT2 (CDC73) (Parafibromin (CDC73))

Autre désignation: CDC73 (CDC73 Produits)

Synonymes: anticorps C1orf28, anticorps HPTJT, anticorps HRPT2, anticorps HYX, anticorps 8430414L16Rik, anticorps BC027756, anticorps C130030P16Rik, anticorps C81219, anticorps Hrpt2, anticorps hrpt2, anticorps zgc:63956, anticorps MGC108428, anticorps cdc73, anticorps LOC100222932, anticorps cell division cycle 73, anticorps cell division cycle 73, Paf1/RNA polymerase II complex component, anticorps cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae), anticorps parafibromin, anticorps cell division cycle 73 S homeolog, anticorps CDC73, anticorps Cdc73, anticorps cdc73, anticorps Tsp_03925, anticorps Tsp_04052, anticorps Tsp_04125, anticorps cdc73.S

Sujet: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Alias Symbols: C1orf28, FLJ23316, HPTJT, HRPT2, HYX
Protein Interaction Partner: CCDC155, FSD2, TSGA10, CEP70, VPS37B, MTUS2, UBC, TFCP2, GOLGA2, ALAS1, CIAO1, AURKB, GPRASP2, COG3, MYH14, MYL12A, ARFGEF2, NUP98, MYH9, CHUK, DNMT3B, DNMT3A, SOX2, BCL9L, PAF1, CTR9, TCF4, CTNNB1, LEO1, GTF2F1, SUV39H1, PTPN11, WDR61, HIST1H3A, RNF20, R
Protein Size: 531

Poids moléculaire: 58 kDa

ID gène: 79577

NCBI Accession: NM_024529, NP_078805

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance