PRKAG3 anticorps (N-Term)

N° du produit ABIN2789710

Cet anticorps Lapin Polyclonal détecte spécifiquement PRKAG3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PRKAG3 anticorps (N-Term) (ABIN2789710)

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAG3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRKAG3 anticorps

Épitope: N-Term

Fonction: PRKAG3 Antibody - N-terminal region

Séquence: ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRKAG3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64048-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRKAG3

Antigène: PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))

Autre désignation: PRKAG3

Sujet:

Targeted Subunit: gamma-3

Background Information: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Gene Name: Protein kinase, AMP-activated, gamma 3 non-catalytic subunit

Alternative Symbols: AMPKG3, SMGMQTL

Protein Name: 5'-AMP-activated protein kinase subunit gamma-3

Poids moléculaire: 54kDa

ID gène: 53632

NCBI Accession: NP_059127

UniProt: Q9UGI9

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, L'effet Warburg