CILP anticorps (C-Term)

N° du produit ABIN970398

Détail du produit anti-CILP anticorps

Antigène: CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien, Cheval, Porc, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CILP est non-conjugé

Application: Western Blotting (WB)

Séquence: YIKVKIVGPL EVNVRSRNMG GTHRQTVGKL YGIRDVRSTR DRDQPNVSAA

Homologie: Cow: 86%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CILP. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1184 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CILP

Antigène: CILP (Cartilage Intermediate Layer Protein, Nucleotide Pyrophosphohydrolase (CILP))

Autre désignation: CILP (CILP Produits)

Synonymes: anticorps CILP-1, anticorps HsT18872, anticorps 9830114D16, anticorps C130036G17Rik, anticorps NTPPH, anticorps CILP, anticorps im:7137994, anticorps cartilage intermediate layer protein, anticorps cartilage intermediate layer protein, nucleotide pyrophosphohydrolase, anticorps cartilage intermediate layer protein 1, anticorps CILP, anticorps Cilp, anticorps cilp, anticorps LOC100336614

Sujet: Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins, an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
Alias Symbols: CILP-1, HsT18872
Protein Interaction Partner: NEDD1, CDC20,
Protein Size: 1184

Poids moléculaire: 52 kDa

ID gène: 8483

NCBI Accession: NM_003613, NP_003604

UniProt: O75339