SNTA1 anticorps (N-Term)

N° du produit ABIN2790311

Détail du produit anti-SNTA1 anticorps

Antigène: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNTA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SPGPTPRNFS EAKHMSLKMA YVSKRCTPND PEPRYLEICS ADGQDTLFLR

Homologie: Cow: 79%, Guinea Pig: 86%, Horse: 82%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SNTA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human SNTA1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SNTA1

Antigène: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Autre désignation: SNTA1 (SNTA1 Produits)

Synonymes: anticorps SNTA1, anticorps MGC147484, anticorps AW228934, anticorps Snt1, anticorps LQT12, anticorps SNT1, anticorps TACIP1, anticorps dJ1187J4.5, anticorps syntrophin alpha 1, anticorps syntrophin, alpha 1 L homeolog, anticorps syntrophin, alpha 1, anticorps syntrophin, acidic 1, anticorps SNTA1, anticorps snta1.L, anticorps snta1, anticorps Snta1

Sujet: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.
Alias Symbols: SNT1, LQT12, TACIP1, dJ1187J4.5
Protein Size: 396

Poids moléculaire: 43 kDa

ID gène: 6640

NCBI Accession: NM_003098, NP_003089

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development