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DOK2 anticorps (C-Term)

DOK2 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN184203
  • Antigène Voir toutes DOK2 Anticorps
    DOK2
    Épitope
    • 22
    • 22
    • 15
    • 9
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 111
    • 78
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval
    Hôte
    • 125
    • 1
    Lapin
    Clonalité
    • 125
    • 1
    Polyclonal
    Conjugué
    • 40
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Cet anticorp DOK2 est non-conjugé
    Application
    • 99
    • 52
    • 52
    • 40
    • 26
    • 20
    • 12
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    QEPRGEAWRR QATRDRDPAG LQHVQPAGQD FSASGWQPGT EYDNVVLKKG
    Homologie
    Cow: 100%, Dog: 90%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 100%, Rat: 90%
    Attributs du produit
    This is a rabbit polyclonal antibody against DOK2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2
    Top Product
    Discover our top product DOK2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 412 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    DOK2
    Autre désignation
    DOK2 (DOK2 Produits)
    Synonymes
    anticorps DokR, anticorps Frip, anticorps Dok-2, anticorps p56DOK, anticorps p56dok-2, anticorps docking protein 2, anticorps DOK2, anticorps Dok2
    Sujet
    DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
    Alias Symbols: p56DOK, p56dok-2
    Protein Interaction Partner: UBC, RASA1, ABL1, POT1, EGFR, KIAA1279, INPP5D, NCK1, TEK, SRC, LYN, RET, LCK, IL4R, HCK, HSPA4L, ASF1B, DNAJB11, RAB10, SSSCA1, CFLAR, SPOP, SHC1, PSMD10, DOK1,
    Protein Size: 412
    Poids moléculaire
    45 kDa
    ID gène
    9046
    NCBI Accession
    NM_003974, NP_003965
    UniProt
    O60496
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