CHRNB3 anticorps (Middle Region)
-
- Antigène Voir toutes CHRNB3 Anticorps
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
-
Épitope
- Middle Region
-
Reactivité
- Souris, Rat, Chien, Lapin, Cobaye, Cheval, Boeuf (Vache)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CHRNB3 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- YDGTMVDLIL INENVDRKDF FDNGEWEILN AKGMKGNRRD GVYSYPFITY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CHRNB3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB3
- Top Product
- Discover our top product CHRNB3 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 458 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
- Autre désignation
- CHRNB3 (CHRNB3 Produits)
- Synonymes
- anticorps 5730417K16Rik, anticorps Acrb3, anticorps NACHR, anticorps CHRNB3, anticorps chrnb3, anticorps cholinergic receptor nicotinic beta 3 subunit, anticorps neuronal acetylcholine receptor subunit beta-3, anticorps cholinergic receptor, nicotinic, beta polypeptide 3, anticorps cholinergic receptor, nicotinic beta 3 L homeolog, anticorps cholinergic receptor, nicotinic beta 3, anticorps cholinergic receptor, nicotinic, beta 3b (neuronal), anticorps cholinergic receptor, nicotinic, beta polypeptide 3a, anticorps CHRNB3, anticorps CpipJ_CPIJ012638, anticorps Chrnb3, anticorps chrnb3.L, anticorps chrnb3, anticorps chrnb3b, anticorps chrnb3a
- Sujet
-
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction.
Protein Size: 458 - Poids moléculaire
- 53 kDa
- ID gène
- 1142
- NCBI Accession
- NM_000749, NP_000740
- UniProt
- Q05901
-