Nucleobindin 1 anticorps (C-Term)

N° du produit ABIN2792699

Détail du produit anti-Nucleobindin 1 anticorps

Antigène: Nucleobindin 1 (NUCB1)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nucleobindin 1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PAAHPEGQLK FHPDTDDVPV PAPAGDQKEV DTSEKKLLER LPEVEVPQHL

Réactivité croisée: Humain

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NUCB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 461 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Nucleobindin 1 (ABIN2792699)

Larkin, Costantino, Seaman, Lavoie: "Calnuc Function in Endosomal Sorting of Lysosomal Receptors." dans: Traffic (Copenhagen, Denmark), Vol. 17, Issue 4, pp. 416-32, (2016) (PubMed).

Détails sur Nucleobindin 1

Antigène: Nucleobindin 1 (NUCB1)

Autre désignation: Nucleobindin-1 (NUCB1 Produits)

Synonymes: anticorps nuc, anticorps MGC69294, anticorps MGC81496, anticorps NUCB1, anticorps zgc:153192, anticorps DKFZp459O1814, anticorps B230337F23Rik, anticorps C77483, anticorps Calnuc, anticorps MTEST82, anticorps Nucb, anticorps CALNUC, anticorps NUC, anticorps nucleobindin 1, anticorps nucleobindin 1 S homeolog, anticorps nucb1, anticorps nucb1.S, anticorps NUCB1, anticorps Nucb1

Sujet: Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot.
Alias Symbols: NUC, CALNUC
Protein Interaction Partner: REL, UBC, MDM2, CTPS2, RAD23B, PRKDC, METTL1, GTF2I, CBS, XPNPEP1, WARS, PTGS2, XPO1, SET, RBL1, MYC, HIVEP1, GNAS, GNAI3, GNAI1, KLC4, PTGS1, NDN, GNAI2, GNAO1, GNAZ,
Protein Size: 461

Poids moléculaire: 51 kDa

ID gène: 4924

NCBI Accession: NM_006184, NP_006175

UniProt: Q02818