PAK1 anticorps (pThr423)

N° du produit ABIN2794204

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK1 dans IF et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour PAK1 anticorps (pThr423) (ABIN2794204)

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1 est non-conjugé

Application: Immunofluorescence (IF), Dot Blot (DB)

Détail du produit anti-PAK1 anticorps

Épitope: pThr423

Fonction: Rabbit Anti-Human Phospho-PAK1(T423) Antibody

Immunogène: This PAK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T423 of human PAK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Immunofluorescence, Dot Blot
Recommended Dilutions
IF: 1:10-50, DB: 1:500Confocal immunofluorescent analysis of Phospho-PAK1-pT423 Antibody on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.460 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PAK1

Antigène: PAK1 (P21-Activated Kinase 1 (PAK1))

Autre désignation: PAK1

Sujet:

Target Description: PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.

Gene Symbol: PAK1

Poids moléculaire: 60647 Da

ID gène: 5058

UniProt: Q13153

Pathways: Signalisation MAPK, Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis