KIR2DL2 anticorps (C-Term)
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- Antigène Voir toutes KIR2DL2 Anticorps
- KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
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Épitope
- AA 263-291, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp KIR2DL2 est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Fonction
- Rabbit Anti-Human KIR2DL2 (C-Term) Antibody
- Immunogène
- This KIR2DL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-291 amino acids from the C-terminal region of human KIR2DL2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product KIR2DL2 Anticorps primaire
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- Indications d'application
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Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50KIR2DL2 Antibody (C-Term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.320 mg/mL
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Antigène
- KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))
- Autre désignation
- KIR2DL2 (KIR2DL2 Produits)
- Synonymes
- anticorps NKAT6, anticorps p58.2, anticorps CD158b, anticorps CD158B1, anticorps killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2, anticorps KIR2DL2
- Sujet
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Target Description: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Gene Symbol: KIR2DL2
- Poids moléculaire
- 38472 Da
- ID gène
- 3803
- UniProt
- P43627
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