NFkB anticorps (C-Term)

N° du produit ABIN2795621

L’anticorps Lapin Polyclonal anti-NFkB a été validé pour WB. Il convient pour détecter NFkB dans des échantillons de Humain.

Aperçu rapide pour NFkB anticorps (C-Term) (ABIN2795621)

Antigène: NFkB (Nuclear Factor kappa B (NFkB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFkB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NFkB anticorps

Épitope: AA 911-937, C-Term

Fonction: Rabbit Anti-Human NFKB(p105) (C-term S933) Antibody

Immunogène: This NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-937 amino acids from the C-terminal region of human NFKB(p105).

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000NFKB(p105) Antibody (C-term S933) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.500 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur NFkB

Antigène: NFkB (Nuclear Factor kappa B (NFkB))

Autre désignation: NFKB

Sujet:

Target Description: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Gene Symbol: NFKB1

Poids moléculaire: 105356 Da

ID gène: 4790

UniProt: P19838

Pathways: Ubiquitin Proteasome Pathway, S100 Proteins