EGF anticorps (C-Term)

N° du produit ABIN2796844

Cet anticorps Souris Monoclonal détecte spécifiquement EGF dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour EGF anticorps (C-Term) (ABIN2796844)

Antigène: EGF (Epidermal Growth Factor (EGF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EGF est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EGF anticorps

Épitope: AA 1163-1191, C-Term

Fonction: Mouse Anti-Human EGFR (C-term) Antibody

Immunogène: This EGFR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000EGFR Antibody (C-term) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.500 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur EGF

Antigène: EGF (Epidermal Growth Factor (EGF))

Autre désignation: EGF

Sujet:

Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Gene Symbol: EGFR

Poids moléculaire: 134277 Da

ID gène: 1956

UniProt: P00533

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation