RFXANK anticorps (Center)

N° du produit ABIN2798940

Détail du produit anti-RFXANK anticorps

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Épitope: AA 94-123, Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFXANK est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit Anti-Human RFXANK (Center) Antibody

Immunogène: This RFXANK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human RFXANK.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000RFXANK Antibody (Center) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur RFXANK

Antigène: RFXANK (Regulatory Factor X-Associated Ankyrin Containing Protein (RFXANK))

Autre désignation: RFXANK (RFXANK Produits)

Synonymes: anticorps ANKRA1, anticorps BLS, anticorps F14150_1, anticorps RFX-B, anticorps Tvl1, anticorps regulatory factor X associated ankyrin containing protein, anticorps regulatory factor X-associated ankyrin-containing protein, anticorps RFXANK, anticorps Rfxank

Sujet:

Target Description: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.

Gene Symbol: RFXANK

Poids moléculaire: 28102 Da

ID gène: 8625

UniProt: O14593