LCMV Protein Z (AA 21-80) anticorps (Alexa Fluor 594)

N° du produit ABIN2803729

Détail du produit

Antigène: LCMV Protein Z

Épitope: AA 21-80

Reactivité: Lymphotic Choriomeniningitis Virus (LCMV), Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Virus

Réactivité croisée (Details): Armstrong Strain LCMV

Attributs du produit: Antibody is specific for: Armstrong Strain LCMV

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from LCMV Protein Z

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LCMV Protein Z

Classe de substances: Viral Protein

Sujet:

Synonyms: Lymphocytic choriomeningitis virus.RING finger protein Z, Protein Z, Zinc-binding protein, Z_LYCVA.

Background: Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (By similarity). Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, step that requires myristoylation of protein Z. Also selectively represses protein production by associating with host eIF4E

UniProt: P18541