PKMYT1 anticorps (AA 121-220) (Alexa Fluor 594)
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- Antigène Voir toutes PKMYT1 Anticorps
- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
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Épitope
- AA 121-220
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PKMYT1 est conjugé à/à la Alexa Fluor 594
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Dog,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human PKMYT1
- Isotype
- IgG
- Top Product
- Discover our top product PKMYT1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))
- Autre désignation
- PKMYT1 (PKMYT1 Produits)
- Synonymes
- anticorps MYT1, anticorps 6230424P17, anticorps AW209059, anticorps Myt1, anticorps RGD1305434, anticorps myt1, anticorps protein kinase, membrane associated tyrosine/threonine 1, anticorps protein kinase, membrane associated tyrosine/threonine 1 S homeolog, anticorps PKMYT1, anticorps pkmyt1, anticorps Pkmyt1, anticorps pkmyt1.S
- Sujet
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Synonyms: cdc2 inhibitory kinase, Membrane associated tyrosine and threonine specic cdc2 inhibitory kinase, Membrane-associated tyrosine- and threonine-specic cdc2-inhibitory kinase, MYT1, Myt1 kinase, PKMYT 1, Pkmyt1, PMYT1_HUMAN, Protein kinase membrane associated tyrosine/threonine 1, Protein kinase Myt1, DKFZp547K1610, FLJ20093.
Background: PKMYT1 is a member of the serine/threonine protein kinase family. It preferentially phosphorylates and inactivates cell division cycle 2 protein (cdc2), and thus acts as a negative regulator of entry into mitosis (G2 to M transition). It mediates phosphorylation of cdc2 predominantly on 'Thr-14' and is also involved in Golgi fragmentation. It may be involved in phosphorylation of cdc2 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. It may be a downstream target of Notch signaling pathway during eye development. PKMYT1 is negatively regulated by hyperphosphorylation during mitosis.
- ID gène
- 9088
- Pathways
- Mitotic G1-G1/S Phases, M Phase
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