RAB5 anticorps (AA 8-100) (Alexa Fluor 594)
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- Antigène Voir toutes RAB5 (RAB5A) Anticorps
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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Épitope
- AA 8-100
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RAB5 est conjugé à/à la Alexa Fluor 594
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris
- Homologie
- Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human RAB5.
- Isotype
- IgG
- Top Product
- Discover our top product RAB5A Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
- Autre désignation
- RAB5 (RAB5A Produits)
- Synonymes
- anticorps RAB5, anticorps 2410015H04Rik, anticorps AI663973, anticorps AU021172, anticorps nnyRab5a, anticorps DDBDRAFT_0168594, anticorps DDBDRAFT_0229401, anticorps DDB_0168594, anticorps DDB_0229401, anticorps rab5, anticorps RAB5A, anticorps Rab5a, anticorps rab5al, anticorps zgc:56644, anticorps fj38g08, anticorps hm:zehn1144, anticorps rab5a, anticorps wu:fj38g08, anticorps RAB5A, member RAS oncogene family, anticorps rab5A protein, anticorps Rab5a, GTPase, anticorps predicted protein, anticorps Rab GTPase, anticorps RAB5A, member RAS oncogene family L homeolog, anticorps RAB5A, member RAS oncogene family, b, anticorps RAB5A, member RAS oncogene family, a, anticorps RAB5A, anticorps Rab5a, anticorps rab5A, anticorps rab5a, anticorps rab5a.L, anticorps rab5ab, anticorps rab5aa
- Sujet
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Synonyms: RAB 5, RAB 5A, RAB5A, RAB5A member RAS oncogene family, RAB5A_HUMAN, RAS associated protein RAB5A, Ras related protein Rab 5A, Ras-related protein Rab-5A.
Background: Rab5-related subfamily. This subfamily includes Rab5 and Rab22 of mammals, Ypt51/Ypt52/Ypt53 of yeast, and RabF of plants. The members of this subfamily are involved in endocytosis and endocytic-sorting pathways. In mammals, Rab5 GTPases localize to early endosomes and regulate fusion of clathrin-coated vesicles to early endosomes and fusion between early endosomes. In yeast, Ypt51p family members similarly regulate membrane trafficking through prevacuolar compartments. GTPase activating proteins (GAPs) interact with GTP-bound Rab and accelerate the hydrolysis of GTP to GDP. Guanine nucleotide exchange factors (GEFs) interact with GDP-bound Rabs to promote the formation of the GTP-bound state. Rabs are further regulated by guanine nucleotide dissociation inhibitors (GDIs), which facilitate Rab recycling by masking C-terminal lipid binding and promoting cytosolic localization. Most Rab GTPases contain a lipid modification site at the C-terminus, with sequence motifs CC, CXC, or CCX. Lipid binding is essential for membrane attachment, a key feature of most Rab proteins. Due to the presence of truncated sequences in this CD, the lipid modification site is not available for annotation.
- ID gène
- 5868
- Pathways
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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