SMARCD3 anticorps (Alexa Fluor 594)

N° du produit ABIN2806502

Détail du produit anti-SMARCD3 anticorps (Alexa Fluor 594)

Antigène: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCD3 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SMARCD3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SMARCD3

Antigène: SMARCD3 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 3 (SMARCD3))

Autre désignation: SMARCD3 (SMARCD3 Produits)

Synonymes: anticorps SMARCD3, anticorps baf60c, anticorps cracd3, anticorps rsc6p, anticorps BAF60C, anticorps CRACD3, anticorps Rsc6p, anticorps 1500001J14Rik, anticorps 2210409C08Rik, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 S homeolog, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b, anticorps SMARCD3, anticorps smarcd3.S, anticorps Smarcd3, anticorps smarcd3b

Sujet:

Synonyms: 60 kDa BRG 1/Brm associated factor subunit C, 60 kDa BRG-1/Brm-associated factor subunit C, BAF60C, BRG1 associated factor 60C, BRG1-associated factor 60C, CRACD3, MGC111010, Rsc6p, Smarcd3, SMRD3_HUMAN, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily d member 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3.

Background: SMARCD3, is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors.

ID gène: 6604

Pathways: Regulation of Lipid Metabolism by PPARalpha