Dihydrofolate Reductase anticorps (AbBy Fluor® 594)

N° du produit ABIN2808570

Cet anticorps Lapin Polyclonal détecte spécifiquement Dihydrofolate Reductase dans IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Dihydrofolate Reductase anticorps (AbBy Fluor® 594) (ABIN2808570)

Antigène: Dihydrofolate Reductase (DHFR)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dihydrofolate Reductase est conjugé à/à la AbBy Fluor® 594

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Dihydrofolate Reductase anticorps (AbBy Fluor® 594)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DHFR

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4°C

Date de péremption: 12 months

Détails sur Dihydrofolate Reductase

Antigène: Dihydrofolate Reductase (DHFR)

Autre désignation: DHFR

Sujet:

DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.

Synonyms: DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR_HUMAN, EC 1.5.1.3.

ID gène: 1719

Pathways: Mitotic G1-G1/S Phases