GRIA2 anticorps (pSer880) (Alexa Fluor 594)

N° du produit ABIN2814033

Détail du produit anti-GRIA2 anticorps (Alexa Fluor 594)

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Épitope: pSer880

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Homologie: Human,Mouse,Rat,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Gria2 around the phosphorylation site of Ser880

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: Gria2 (GRIA2 Produits)

Synonymes: anticorps GLUR2, anticorps GLURB, anticorps GluA2, anticorps GluR-K2, anticorps HBGR2, anticorps GluR-2, anticorps GluR-B, anticorps Glur-2, anticorps Glur2, anticorps GluR2, anticorps gluR-B, anticorps glur2a, anticorps gria2.1, anticorps zfGRIA2[a], anticorps glur2, anticorps glutamate ionotropic receptor AMPA type subunit 2, anticorps glutamate receptor, ionotropic, AMPA 2, anticorps glutamate receptor, ionotropic, AMPA2 (alpha 2), anticorps glutamate receptor, ionotropic, AMPA 2a, anticorps glutamate receptor, ionotropic, AMPA 2 S homeolog, anticorps GRIA2, anticorps Gria2, anticorps gria2a, anticorps gria2.S

Sujet:

Synonyms: Glutamate receptor 2 PrecursorSer880, Gria2, Glur-2, GluR-B, Glur2, GluR-2, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2, glutamate receptor, ionotropic, N-methyl D-aspartate 1, NMDA receptor subunit , AMPA-selective glutamate receptor 2.

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG, Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.

ID gène: 2891

Pathways: Signalisation PI3K-Akt