BRAF anticorps (pThr400)

N° du produit ABIN389897

Il existe 1 publication pour ce produit. L’anticorps anti-BRAF Polyclonal Lapin est utilisé pour la détection de BRAF dans des échantillons de Humain. Il a été validé pour DB.

Aperçu rapide pour BRAF anticorps (pThr400) (ABIN389897)

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRAF est non-conjugé

Application: Dot Blot (DB)

Clone: RB13721

Détail du produit anti-BRAF anticorps

Épitope: pThr400

Specificité: This Phospho-BRAF-pT400 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.

Homologie: Mouse (Murine)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T400 of human BRAF.

Isotype: Ig Fraction

Information d'application

Indications d'application: DB = 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-BRAF (ABIN389897)

Duan, Cobb: "Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 51, pp. 22314-9, (2010) (PubMed).

Détails sur BRAF

Antigène: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Autre désignation: BRAF

Sujet: BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Synonyms: B-Raf proto-oncogene serine/threonine-protein kinase, p94, v-Raf murine sarcoma viral oncogene homolog B1

Poids moléculaire: 84437 DA

ID gène: 673

UniProt: P15056

Pathways: Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy