CENPF anticorps (C-Term)

N° du produit ABIN2854654

Cet anticorps Lapin Polyclonal détecte spécifiquement CENPF dans WB, IHC (p), IF, ICC et IHC (wm). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour CENPF anticorps (C-Term) (ABIN2854654)

Antigène: CENPF (Centromere Protein F (CENPF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))

Détail du produit anti-CENPF anticorps

Épitope: C-Term

Réactivité croisée: Humain, Poisson zèbre (Danio rerio)

Attributs du produit: Rabbit Polyclonal antibody to CENPF (centromere protein F, 350/400 kDa (mitosin))
CENPF antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CENPF. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-CENPF (ABIN2854654)

Chen, Lin, Cheng, Lin, Lo, Yen, Lee, Hsiao: "Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish." dans: Oncotarget, Vol. 5, Issue 15, pp. 6300-11, (2015) (PubMed).

Détails sur CENPF

Antigène: CENPF (Centromere Protein F (CENPF))

Autre désignation: centromere protein F

Sujet: This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Cellular Localization: Cytoplasm , perinuclear region , Nucleus matrix , Kinetochore , Spindle

Poids moléculaire: 368 kDa

ID gène: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2