PPP2R1A anticorps (Center)

N° du produit ABIN2855322

Détail du produit anti-PPP2R1A anticorps

Antigène: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Rat (Rattus), Porc, Macaque rhésus

Réactivité croisée (Details): Rat (100 %), Pig (100 %), Rhesus Monkey (100 %)

Attributs du produit: Rabbit Polyclonal antibody to PPP2R1A (serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform)
PPP2R1A antibody

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PPP2R1A. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:1000-1:10000*

Commentaires:

Positive Control: HeLa , NIH-3T3 , JC , BCL-1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-PPP2R1A (ABIN2855322)

Yen, Chien, Lai, Chen, Chuong, Hung, Hung: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." dans: Cells, Vol. 9, Issue 1, (2020) (PubMed).

Détails sur PPP2R1A

Antigène: PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))

Autre désignation: PPP2R1A (PPP2R1A Produits)

Synonymes: anticorps PP2A-Aalpha, anticorps PP2AAALPHA, anticorps PR65A, anticorps PR65, anticorps pp2a-aalpha, anticorps pp2aaalpha, anticorps ppp2r1a, anticorps pr65a, anticorps wu:fa02h04, anticorps zgc:56296, anticorps 6330556D22Rik, anticorps PP2A, anticorps ppp2r1a-a, anticorps ppp2r1a-b, anticorps protein phosphatase 2 scaffold subunit Aalpha, anticorps protein phosphatase 2 scaffold subunit A alpha, anticorps protein phosphatase 2 regulatory subunit A, alpha L homeolog, anticorps protein phosphatase 2 regulatory subunit A, alpha, anticorps protein phosphatase 2, regulatory subunit A, beta a, anticorps serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, anticorps protein phosphatase 2, regulatory subunit A, alpha isoform, anticorps protein phosphatase 2, regulatory subunit A, alpha, anticorps protein phosphatase 2 regulatory subunit A, alpha S homeolog, anticorps PPP2R1A, anticorps Ppp2r1a, anticorps ppp2r1a.L, anticorps ppp2r1a, anticorps ppp2r1ba, anticorps LOC583227, anticorps ppp2r1a.S

Sujet: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A.

Poids moléculaire: 65 kDa

ID gène: 5518

Pathways: Signalisation PI3K-Akt, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades