SERPING1 anticorps (Center)

N° du produit ABIN2856082

Détail du produit anti-SERPING1 anticorps

Antigène: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Épitope: Center

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SERPING1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Attributs du produit: Rabbit Polyclonal antibody to C1 inhibitor (serpin peptidase inhibitor, clade G (C1 inhibitor), member 1)
C1 inhibitor antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human C1 inhibitor. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Immunohistochemistry Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceImmunohistochemistryAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Commentaires:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Références pour anticorps anti-SERPING1 (ABIN2856082)

Kwon, Kim, Hwang, Kim, Kim, Kim, Lee, Im, Lee, Hwang: "Generation of α-1,3-galactosyltransferase knocked-out transgenic cloned pigs with knocked-in five human genes." dans: Transgenic research, Vol. 26, Issue 1, pp. 153-163, (2018) (PubMed).

Hayashi, Ushizawa, Hosoe, Takahashi: "Differential gene expression of serine protease inhibitors in bovine ovarian follicle: possible involvement in follicular growth and atresia." dans: Reproductive biology and endocrinology : RB&E, Vol. 9, pp. 72, (2011) (PubMed).

Détails sur SERPING1

Antigène: SERPING1 (Serpin Peptidase Inhibitor, Clade G (C1 Inhibitor), Member 1 (SERPING1))

Autre désignation: C1 Inhibitor (SERPING1 Produits)

Synonymes: anticorps fb64f02, anticorps im:7159527, anticorps si:dkeyp-110g5.2, anticorps wu:fb60c09, anticorps wu:fb62a08, anticorps wu:fb64f02, anticorps LOC100136072, anticorps C1-INH, anticorps C1INH, anticorps C1nh, anticorps C1IN, anticorps C1NH, anticorps HAE1, anticorps HAE2, anticorps serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, anticorps C1 inhibitor, anticorps serpin family G member 1, anticorps serine (or cysteine) peptidase inhibitor, clade G, member 1, anticorps serping1, anticorps LOC100136072, anticorps SERPING1, anticorps Serping1

Sujet: This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Cellular Localization: Secreted

Poids moléculaire: 55 kDa

ID gène: 710

Pathways: Système du Complément