TP53I3 anticorps

N° du produit ABIN2856195

Détail du produit anti-TP53I3 anticorps

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53I3 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to PIG3 (tumor protein p53 inducible protein 3)
PIG3 antibody [N2C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PIG3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: A549

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TP53I3

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Autre désignation: tumor protein p53 inducible protein 3 (TP53I3 Produits)

Synonymes: anticorps MGC82892, anticorps MGC146409, anticorps PIG3, anticorps tumor protein p53 inducible protein 3, anticorps tumor protein p53 inducible protein 3 S homeolog, anticorps Tp53I3, anticorps quinone oxidoreductase PIG3, anticorps TP53I3, anticorps tp53i3.S, anticorps tp53i3, anticorps tp53I3

Sujet: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 36 kDa

ID gène: 9540

UniProt: Q53FA7

Pathways: Signalisation p53