PDK1 anticorps

N° du produit ABIN2856238

Cet anticorps Lapin Polyclonal détecte spécifiquement PDK1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PDK1 anticorps (ABIN2856238)

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDK1 anticorps

Specificité: Based on sequence homology, this antibody may cross react with other PDK family members.

Réactivité croisée: Humain

Attributs du produit: Rabbit polyclonal antibody to PDK1 (pyruvate dehydrogenase kinase, isozyme 1)
PDK1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Pyruvate dehydrogenase kinase 1 / PDK1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLaS3 , Molt-4 , human PDK1 transfected 293T cells

Validation: Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur PDK1

Antigène: PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))

Autre désignation: pyruvate dehydrogenase kinase 1

Sujet: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.

Cellular Localization: Mitochondrion matrix

Poids moléculaire: 49 kDa

ID gène: 5163

UniProt: Q15118

Pathways: Signalisation PI3K-Akt, Signalisation RTK, Regulation of Carbohydrate Metabolic Process, Hepatitis C, L'effet Warburg