ATP6V0A4 anticorps (N-Term)

N° du produit ABIN2856797

Détail du produit anti-ATP6V0A4 anticorps

Antigène: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V0A4 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Boeuf (Vache)

Réactivité croisée (Details): Mouse (87 %), Bovine (82 %)

Attributs du produit: Rabbit polyclonal antibody to V-ATPase 116 kDa isoform a4 (ATPase, H+ transporting, lysosomal V0 subunit a4)
V-ATPase 116 kDa isoform a4 antibody [N1N3-2]

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human V-ATPase 116 kDa isoform a4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Commentaires:

Positive Control: A431 , HeLa , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ATP6V0A4

Antigène: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Autre désignation: V-ATPase 116 kDa Isoform a4 (ATP6V0A4 Produits)

Synonymes: anticorps A4, anticorps ATP6N1B, anticorps ATP6N2, anticorps RDRTA2, anticorps RTA1C, anticorps RTADR, anticorps STV1, anticorps VPH1, anticorps VPP2, anticorps Atp6n1b, anticorps a4, anticorps ATPase H+ transporting V0 subunit a4, anticorps ATPase, H+ transporting, lysosomal V0 subunit A4, anticorps ATP6V0A4, anticorps Atp6v0a4

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.

Cellular Localization: Apical cell membrane, Multi-pass membrane protein

Poids moléculaire: 96 kDa

ID gène: 50617

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport