Nephrin anticorps (AA 1243-1256)

N° du produit ABIN285873

Détail du produit anti-Nephrin anticorps

Antigène: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Épitope: AA 1243-1256

Reactivité: Humain, Souris

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: Cet anticorp Nephrin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Pureté: Whole antiserum

Immunogène: Nephrin antibody was raised in guinea pig using a synthetic peptide corresponding to residues 1243-1256 of the intracellular domain of nephrin as the immunogen.

Isotype: IgG1

Information d'application

Indications d'application: IHC-F: 1:50, IHC-P: 1:50, WB: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid with 0.09 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Stock: 4 °C

Stockage commentaire: Store at 4 °C

Références pour anticorps anti-Nephrin (ABIN285873)

Zhou, Chen, Lu, Wu, Yuan, Hu, Miao, Zhang, Li, Hou, Nie, Liu: "Wnt/β-catenin links oxidative stress to podocyte injury and proteinuria." dans: Kidney international, Vol. 95, Issue 4, pp. 830-845, (2020) (PubMed).

Eng, Kaverina, Schneider, Freedman, Gross, Miner, Pippin, Shankland: "Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing." dans: Kidney international, Vol. 93, Issue 5, pp. 1240-1246, (2018) (PubMed).

de Groot, Damen, Kosse, Alsady, Doty, Baumgarten, Sheehan, van der Vlag, Korstanje, Deen: "Lithium reduces blood glucose levels, but aggravates albuminuria in BTBR-ob/ob mice." dans: PLoS ONE, Vol. 12, Issue 12, pp. e0189485, (2018) (PubMed).

Beckerman, Bi-Karchin, Park, Qiu, Dummer, Soomro, Boustany-Kari, Pullen, Miner, Hu, Rohacs, Inoue, Ishibe, Saleem, Palmer, Cuervo, Kopp, Susztak: "Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice." dans: Nature medicine, Vol. 23, Issue 4, pp. 429-438, (2017) (PubMed).

Awad, You, Gao, Gvritishvili, Cooper, Tombran-Tink: "Delayed Treatment with a Small Pigment Epithelium Derived Factor (PEDF) Peptide Prevents the Progression of Diabetic Renal Injury." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0133777, (2016) (PubMed).

Badal, Wang, Long, Corcoran, Chang, Truong, Kanwar, Overbeek, Danesh: "miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy." dans: Nature communications, Vol. 7, pp. 12076, (2016) (PubMed).

Aggarwal, Veron, Thomas, Siegel, Moeckel, Kashgarian, Tufro: "Semaphorin3a promotes advanced diabetic nephropathy." dans: Diabetes, Vol. 64, Issue 5, pp. 1743-59, (2015) (PubMed).

Veron, Villegas, Aggarwal, Bertuccio, Jimenez, Velazquez, Reidy, Abrahamson, Moeckel, Kashgarian, Tufro: "Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus." dans: PLoS ONE, Vol. 7, Issue 7, pp. e40589, (2013) (PubMed).

Veron, Bertuccio, Marlier, Reidy, Garcia, Jimenez, Velazquez, Kashgarian, Moeckel, Tufro: "Podocyte vascular endothelial growth factor (Vegf₁₆₄) overexpression causes severe nodular glomerulosclerosis in a mouse model of type 1 diabetes." dans: Diabetologia, Vol. 54, Issue 5, pp. 1227-41, (2011) (PubMed).

Détails sur Nephrin

Antigène: Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))

Autre désignation: Nephrin (NPHS1 Produits)

Synonymes: anticorps NPHS1, anticorps nphs1l, anticorps nphs1, anticorps CNF, anticorps NPHN, anticorps nephrin, anticorps NephrinB, anticorps NPHS1, nephrin, anticorps nephrosis 1, congenital, Finnish type (nephrin), anticorps NPHS1 nephrin S homeolog, anticorps nephrin, anticorps NPHS1 nephrin, anticorps nephrosis 1, nephrin, anticorps NPHS1, anticorps nphs1, anticorps nphs1.S, anticorps LOC5579127, anticorps Nphs1

Pathways: Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development