IL12 anticorps (Biotin)
Aperçu rapide pour IL12 anticorps (Biotin) (ABIN288430)
Antigène
Voir toutes IL12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Immunogène
- IL12 antibody (biotin) was raised in goat using highly pure recombinant human IL-12 as the immunogen.
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Indications d'application
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ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2, with 0.1 % BSA.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IL12 (Interleukin 12 (IL12))
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Autre désignation
- IL12
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Sujet
- IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells.
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Poids moléculaire
- 75 kDa (predicted detection band MW)
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Pathways
- Signalistation JAK/STAT, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Antigène
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