IFNB1 anticorps
Aperçu rapide pour IFNB1 anticorps (ABIN289463)
Antigène
Voir toutes IFNB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Attributs du produit
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Affinity purified Goat polyclonal IFN beta antibody
Bioactivity: The exact concentration of antibody required to neutralize human interferon beta activity is dependent on the cytokine concentration, cell type, growth conditions and type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. The ND50 for this antibody on human (HeLa/EMCV) cells is approx. 0.05- 0.2 µg/mL in the presence of 10ng/mL of human interferon beta, based on the anti-viral assay. The specific conditions are described in the figure legends. -
Purification
- Purified
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Immunogène
- IFN beta antibody was raised in goat using human interferon beta as the immunogen.
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Isotype
- IgG
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Indications d'application
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in sterile PBS.
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS with 5 % trehalose.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C.
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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Autre désignation
- IFN beta
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Sujet
- Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.
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Pathways
- Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
Antigène
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