SLC22A8 anticorps

N° du produit ABIN289968

Détail du produit anti-SLC22A8 anticorps

Antigène: SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A8 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT3 by peptide affinity chromatography.

Immunogène: Partial peptide of Human Organic Anion Transporter 3 (OAT3)

Information d'application

Indications d'application: Working dilution for immunohistochemistry 1-5ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur SLC22A8

Antigène: SLC22A8 (Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8))

Autre désignation: Organic Anion Transporter 3 (OAT3) (SLC22A8 Produits)

Synonymes: anticorps OAT3, anticorps Oat3, anticorps Roct, anticorps OCT3, anticorps solute carrier family 22 member 8, anticorps solute carrier family 22 (organic anion transporter), member 8, anticorps SLC22A8, anticorps Slc22a8

Sujet: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of thebody, specific membrane proteins named transporters are required. There are two major pathways for theelimination, one of which is hepatic one through bile, and another is renal one to urine. The transporter fallinto various transport systems by the transportative substrate. In particular, oraganic ion transporter familyis comprised of organic anion transport family (OAT), oraganic cation transport family (OCT),OCTN/carnitine transport family, and OAT are multispecific organic anion transpoters, the substrates ofwhich include a lot of both endogeneous and exogeneous anions.Human organic anion transporter 3 (OAT3) encodes a 543 amino acid residue protein, and which ispredicted 12 putative membran-spanning protein. OAT3 is expressed in the kidney, brain, and skeletalmuscle. OAT3 mediated the uptake of organic anions, such as PAH (p-aminohippurate), ochratoxin A andestrone sulfate, prostaglandin E2 (PGE2 ), and cimetidine.This has been proved to be useful for immunohistochemistry .