SLC22A6 anticorps

N° du produit ABIN289973

Détail du produit anti-SLC22A6 anticorps

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC22A6 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum immunized with synthesized C-end peptide of human OAT1 by peptide affinity chromatography.

Immunogène: Partial peptide of Human Organic Anion Transporter 1(OAT1)

Information d'application

Indications d'application: Working dilution for immunohistochemistry 5ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur SLC22A6

Antigène: SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))

Autre désignation: Organic Anion Transporter 1(OAT1) (SLC22A6 Produits)

Synonymes: anticorps HOAT1, anticorps OAT1, anticorps PAHT, anticorps ROAT1, anticorps NKT, anticorps Oat1, anticorps Orctl1, anticorps mOat1, anticorps slc22a6, anticorps zgc:77073, anticorps SLC22A6, anticorps Paht, anticorps Roat1, anticorps nkt, anticorps oat1, anticorps oat1-B, anticorps paht, anticorps roat1, anticorps slc22a6-B, anticorps Slc22a6, anticorps solute carrier family 22 member 6, anticorps solute carrier family 22 (organic anion transporter), member 6, anticorps solute carrier family 22 (organic anion transporter), member 6, like, anticorps Solute carrier family 22 member 6, anticorps solute carrier family 22 (organic anion transporter), member 6 S homeolog, anticorps SLC22A6, anticorps Slc22a6, anticorps slc22a6l, anticorps s22a6, anticorps slc22a6.S

Sujet: To eliminate the drug, xenobiotics, a varirety of endogeneous substances, and their metabolites out of the body, specific membrane proteins named transporters are required. There are two major pathways for theelimination, hepatic one through bile and renal one to urine. The transporter fall into various transportsystems by the transportative substrate. In particular, oraganic ion transporter family is comprised oforganic anion transport family (OAT), oraganic cation transport family (OCT), OCTN/carnitine transportfamily, and OAT are multispecific organic anion transpoters, the substrates of which include a lot of bothendogeneous and exogeneous anions .Human Organic anion transporter 1(OAT1) encodes a 563 amino acid residue protein, and which ispredicted 12 putative membrane-spanning protein. Human OAT1 was found to be expressed predominantlyin the kidney and only weakly in the brain. OAT1 mediates the Na+-independent transport of organic anions,such as PAH (p-aminohippurate), cyclic nucleotides, prostanoides, dicaroxylates, and many anion drugs.This antibody has been proved to be useful for immunohistochemistry .

Pathways: Dicarboxylic Acid Transport