PER3 anticorps

N° du produit ABIN289981

Détail du produit anti-PER3 anticorps

Antigène: PER3 (Period Homolog 3 (PER3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER3 est non-conjugé

Application: Western Blotting (WB)

Purification: ProteinG Affinity Purified

Immunogène: GST-Human PERIOD3 fusion Protein

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur PER3

Antigène: PER3 (Period Homolog 3 (PER3))

Autre désignation: PERIOD3 (PER3 Produits)

Synonymes: anticorps period3, anticorps rper3, anticorps GIG13, anticorps 2810049O06Rik, anticorps mPer3, anticorps period circadian clock 3, anticorps period circadian regulator 3, anticorps Per3, anticorps PER3

Sujet: Most organisms show circadian 24-h rhythmicity in their behavior and phsysiology. In mammals,biological clock is located in the suprachiasmatic nucleus (SCN), generates circadian rhythms in behaviourand physiology. These biological rhythms are adjusted daily to the environmental light/dark cycle via theretinohypothalamic tract (RHT). Three mammalian priod genes (per1, per2, and per3) that resemble theclock-regulating gene of Dorosophia melangaster, period (per ), have been cloned. Circadian clocks arealso located in peripheral tissues of mammals that are synchronized by the SCN. A molecular description ofthe mammalian circadian system has revealed that circadian oscillations may be a fundamental property ofmany cells in the body.Recently, it has been shown that the phosphorylation of PER proteins by casein kinase Iepsilon can modulatethe nuclear localization of mPER1 and mPER3 but not of mPER2.This antibody is useful tool to clarify molecular functions that regulate biological clock.