ENPP2 anticorps

N° du produit ABIN290037

Détail du produit anti-ENPP2 anticorps

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENPP2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody was established from the serum of a rabbit immunized with a peptiderepresenting the N-terminal domain of Autotaxin.Purified by peptide affinity chromatography.

Immunogène: Partial peptide of Autotaxin (N-Term)

Information d'application

Indications d'application: Working dilution For Western blotting:0.5ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur ENPP2

Antigène: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Autre désignation: Autotaxin (ENPP2 Produits)

Synonymes: anticorps ATX, anticorps ATX-X, anticorps AUTOTAXIN, anticorps LysoPLD, anticorps NPP2, anticorps PD-IALPHA, anticorps PDNP2, anticorps Npps2, anticorps PD-Ialpha, anticorps Pdnp2, anticorps MGC132047, anticorps atx, anticorps zgc:63550, anticorps autotaxin, anticorps enpp2, anticorps enpp2a, anticorps enpp2b, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog, anticorps ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog, anticorps ENPP2, anticorps Enpp2, anticorps enpp2, anticorps enpp2.L, anticorps enpp2.S

Sujet: Autotaxin, a member of the ENPP (Ectonucleotide pyrophospatase/phosphodiesterase) family ofectoenzymes, was originally identified as a motogen secreted by a melanoma cell line and subsequentlyreported to promote cell proliferation, cell motility, angiogenesis, and neurite retraction. Autotaxin haslysophospholipase D activity and appears to exert its effects by generation of the lipid mediatorlysophosphatidic acid (LPA) from lysophosphatidylcholine and sphingosine 1-phosphate (S1P) fromsphingosylphosphorylcholine (SPC) outside the cell.Autotaxin levels are significantly higher in cancerous tissues than in normal tissues suggesting that thisnovel extracellular protein may be involved in tumor progression.Two Autotaxin antibodies are available,KM105: Specifically reacts with a C-terminal fragment of AutotaxinKM106: Specifically reacts with an N-terminal fragment of Autotaxin