PPARG anticorps

N° du produit ABIN290044

Détail du produit anti-PPARG anticorps

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPARG est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the C-terminal domain of Human PPARgamma, and purified by peptide affinity chromatography.

Immunogène: Partial peptide of Human PPAR gamma

Information d'application

Indications d'application: Working dilution For Western blotting: 1.0ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur PPARG

Antigène: PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

Autre désignation: PPARgamma (PPARG Produits)

Synonymes: anticorps PPAR gamma, anticorps PPARg2, anticorps PPARG, anticorps Nr1c3, anticorps PPAR-gamma, anticorps PPAR-gamma2, anticorps PPARgamma, anticorps PPARgamma2, anticorps NR1C3, anticorps CIMT1, anticorps GLM1, anticorps PPARG1, anticorps PPARG2, anticorps xPPAR-gamma, anticorps PPAR-GAMMA, anticorps PPARGAMMA, anticorps peroxisome proliferator-activated receptor gamma, anticorps peroxisome proliferator activated receptor gamma, anticorps peroxisome proliferator activated receptor gamma L homeolog, anticorps PPARG, anticorps Pparg, anticorps pparg.L

Sujet: PPARs (peroxisome proliferator-activated receptors) are a family of transcription factors belonging tothe nuclear hormone receptor superfamily. Widely expressed in vertebrates, PPARs play critical roles inmetabolism and differentiation of a number of cell types.The PPAR gamma subtype was originally identified as a factor binding to a fatty acid specific enhancer of the aP2 gene. PPAR-gamma actions are mediated by three isoforms resulting from alternative promoter selection andalternative splicing. PPAR-gamma1 is widely expressed while PPAR-gamma2 expression is restricted to adipose tissueand PPAR-gamma3 expression is restricted to adipose tissue, macrophage, and colon.PPAR gamma participates in adipose cell differentiation and energy storage (Ref.1).Recently, these roles of PPARgamma have focused attention on PPARgamma as a target of the anti-diabeticthiazolidinedione class of drugs (Ref.2).

Pathways: Signalisation MAPK, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation